Professional Analytical and Consulting Services

Inductively Coupled Plasma Mass Spectrometry: Principles and Applications

PACS Course Number 25

9 AM to 5 PM

Inductively Coupled Plasma Mass Spectrometry (ICP-MS) is a rapidly growing analytical technique that can help solve a wide variety of problems. The goal of this two-day course is to introduce you to ICP-MS principles, operation, and open your eyes to applications for a variety of sample matrices. This course is designed for managers, chemists, and technicians who are actively involved in trace element analysis. If you have a present or future need for upgrading your trace element analytical capabilities, and you need to know more about the advantages and limitations of ICP-MS, then this course is for you. Participants will come away from this course with a better understanding of basic principles, specific applications, and a framework for critically evaluating the available commercial instruments. An agenda for this course is shown below.

The course instructor is Bill Purves. He has extensive experience with ICP-MS operation, method development, standard operating procedures (SOP) development, maintenance, and applications development. Extensive course notes will be provided. No calculators are required, and the course is not theory oriented. The course is designed to be of quick practical use to the participants. Participants are asked to indicate their special interest on the registration form. The instructor will make every effort to accommodate these interests during your course.

Register by mailing a copy of the REGISTRATION FORM. Send it with a payment of $1995 to secure your attendance. Hotel information and a map will be sent to confirm your registration. Please list your special interest(s) on the registration form. Enrollment is limited to assure your maximum course benefits. On-site PACS courses are available (most PACS courses can be provided at your time and place). Telephone Henry Nowicki or Barb Sherman at 1.724.457.6576 if you need further information. PACS also provides laboratory testing and consulting services.



Inductively Coupled Plasma Mass Spectrometry: Principles and Applications

Course Instructor: Bill Purves under the auspices of PACS

Topics during this two-day course:
Brief history of ICP-MS
Overview of applications
Basic theory of operation
Description of the functional parts of ICP-MS instruments
Detection limits
Multi-element capabilities, calibrations
Sample throughput
Linear working range
Review Periodic table: Stable isotopes of the elements
Select appropriate isotopes for quantitative analysis
Interferences - isobaric, molecular species, matrix suppression or enhancement
Oxides and doubly charged ions
Semi-quantitative analysis using full-scan MS
Quantitative analysis using internal standards
Isotope dilution and isotope ratio ICP-MS
Matrix matching using standard additions
Sample preparation techniques
Sample introduction techniques
Developing a method and SOP
Developing an application
Routine preventive maintenance
Troubleshooting
Daily performance checks, initial and continuing
Description of commercially available instruments
Cost/benefit analysis
Comparison with GFAA - technical and sample capacity
Disadvantages of ICP-MS and how to overcome them
Bibliography of current applications

View the PACS Short Course Schedule

Course participants are encouraged to e-mail questions to Dr. Henry Nowicki at

Please NOTE: List your special interest on the registration form. We will try to accommodate your interest. PACS also provides internet consulting information at http://pacslabs.com

Training is an Investment in employee employer Future!

For more information please contact:

Henry Nowicki, Ph.D. / M.B.A
PACS Testing, Consulting and Training
409 Meade Drive, Coraopolis, PA 15108
Phone: 1. 724. 457. 6576 or 1. 800. 367. 2587
E-Mail:
PACS website: http://pacslabs.com


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